Encodes a group I formin. Binds to F-actin barbed ends. Has severing actin filaments activity. Binds profilin. Involved in the initiation and tip growth of root hairs through regulation of actin cytoskeleton.
Computational Description
formin 8 (FH8); FUNCTIONS IN: actin binding, profilin binding, actin filament binding; INVOLVED IN: actin nucleation, cell tip growth; LOCATED IN: cell-cell junction, plasma membrane; EXPRESSED IN: 17 plant structures; EXPRESSED DURING: 7 growth stages; CONTAINS InterPro DOMAIN/s: Actin-binding FH2/DRF autoregulatory (InterPro:IPR003104), Actin-binding FH2 (InterPro:IPR015425); BEST Arabidopsis thaliana protein match is: formin homologue 4 (TAIR:AT1G24150.1); Has 22376 Blast hits to 12386 proteins in 831 species: Archae - 31; Bacteria - 2621; Metazoa - 7710; Fungi - 2231; Plants - 6132; Viruses - 1038; Other Eukaryotes - 2613 (source: NCBI BLink).