Encodes coproporphyrinogen III oxidase, a key enzyme in the biosynthetic pathway of chlorophyll and heme, a tetrapyrrole pathway. Mutants express cytological and molecular markers associated with the defense responses, usually activated by pathogen infection.
Computational Description
LESION INITIATION 2 (LIN2); FUNCTIONS IN: coproporphyrinogen oxidase activity; INVOLVED IN: tetrapyrrole biosynthetic process; LOCATED IN: apoplast, chloroplast stroma, chloroplast, plastid; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Coproporphyrinogen III oxidase (InterPro:IPR001260), Coproporphyrinogen III oxidase, conserved site (InterPro:IPR018375); BEST Arabidopsis thaliana protein match is: Coproporphyrinogen III oxidase (TAIR:AT4G03205.1); Has 4884 Blast hits to 4875 proteins in 1228 species: Archae - 0; Bacteria - 2144; Metazoa - 115; Fungi - 160; Plants - 86; Viruses - 0; Other Eukaryotes - 2379 (source: NCBI BLink).
