Pyruvate dehydrogenase kinase (PDK) specifically phosphorylates the E1α subunit of the pyruvate dehydrogenase complex (PDC) on a Ser residue using ATP as a phosphate donor. PDK is a unique type of protein kinase having a His-kinase-like sequence but Ser-kinase activity. Site-directed mutagenesis and structural analysis indicate that PDK belongs to the GHKL superfamily.
Protein of unknown function (DUF1423); CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF1423, plant (InterPro:IPR004082); BEST Arabidopsis thaliana protein match is: Protein of unknown function (DUF1423) (TAIR:AT1G14740.1); Has 795 Blast hits to 695 proteins in 144 species: Archae - 6; Bacteria - 39; Metazoa - 207; Fungi - 61; Plants - 263; Viruses - 0; Other Eukaryotes - 219 (source: NCBI BLink).
Protein of unknown function (DUF1423); CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF1423, plant (InterPro:IPR004082); BEST Arabidopsis thaliana protein match is: Protein of unknown function (DUF1423) (TAIR:AT1G14740.1); Has 3195 Blast hits to 2635 proteins in 392 species: Archae - 10; Bacteria - 381; Metazoa - 1310; Fungi - 308; Plants - 351; Viruses - 11; Other Eukaryotes - 824 (source: NCBI BLink).