PFS2 encodes a homeodomain gene that is a member of the WUS clade of transcription factors. It delays differentiation and maturation of primordia and regulates ovule patterning. The pfs2 mutant exhibits developmental defects in the maternal integuments and gametophyte, specifically, the boundary between the chalaza and the nucellus shifted towards the distal end of pfs2 ovule primordia. In addition, leaves displayed curling and petals were wavy and crenulated. Overexpression of PFS2 affects floral organ and leaf development. Single- and double-mutant analyses reveal that PFS2 activity represses AGAMOUS expression in young floral primordia. Also involved in regulation of response to low temperature.
Computational Description
PRETTY FEW SEEDS 2 (PFS2); FUNCTIONS IN: sequence-specific DNA binding transcription factor activity; INVOLVED IN: in 9 processes; LOCATED IN: primary endosperm nucleus, nucleus; EXPRESSED IN: 12 plant structures; CONTAINS InterPro DOMAIN/s: Homeobox (InterPro:IPR001356), Homeodomain-like (InterPro:IPR009057); BEST Arabidopsis thaliana protein match is: WUSCHEL related homeobox 1 (TAIR:AT3G18010.1); Has 564 Blast hits to 564 proteins in 49 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 4; Plants - 560; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink).
