Encodes a novel Armadillo BTB protein that intreacts with the pre-replication complex and several transcription factors. Overexpression results in decreased cell proliferation and loss of function results in increased cell proliferation suggesting a role in negative regulation of cellular proliferation.
Computational Description
ARMADILLO BTB protein 1 (ABAP1); CONTAINS InterPro DOMAIN/s: HEAT (InterPro:IPR000357), Armadillo-like helical (InterPro:IPR011989), BTB/POZ fold (InterPro:IPR011333), Armadillo (InterPro:IPR000225), BTB/POZ (InterPro:IPR013069), Armadillo-type fold (InterPro:IPR016024), BTB/POZ-like (InterPro:IPR000210); BEST Arabidopsis thaliana protein match is: ARM repeat protein interacting with ABF2 (TAIR:AT5G19330.1); Has 15271 Blast hits to 11668 proteins in 362 species: Archae - 10; Bacteria - 68; Metazoa - 9499; Fungi - 805; Plants - 3646; Viruses - 85; Other Eukaryotes - 1158 (source: NCBI BLink).