Induced in response to ionizing radiation, shows basal expression in mitotically active cells and high expression in endoreduplicating cells. May be involved in DNA damage-induced growth arrest. Protein sequence contains a PEST destruction box.
Computational Description
gamma response gene 1 (GR1); INVOLVED IN: meiotic DNA double-strand break processing, response to DNA damage stimulus, gamete generation, response to ionizing radiation; EXPRESSED IN: bud, cultured cell, leaf; EXPRESSED DURING: seedling growth; CONTAINS InterPro DOMAIN/s: DNA repair protein Sae2/CtIP (InterPro:IPR013882); Has 26568 Blast hits to 17186 proteins in 1344 species: Archae - 485; Bacteria - 2739; Metazoa - 14510; Fungi - 2010; Plants - 1072; Viruses - 86; Other Eukaryotes - 5666 (source: NCBI BLink).