Encodes a chloroplast polynucleotide phosphorylase (PNPase). Involved in response to phosphorus (P) starvation. Mutants impaired in the expression of this gene have been selected through their resistance to fosmidomycin, a strong inhibitor of DXR, an enzyme of the methylerythritol-dependent IPP biosynthesis pathway. The pathway enzymes were upregulated in the mutant seedlings.
Computational Description
resistant to inhibition with FSM 10 (RIF10); FUNCTIONS IN: polyribonucleotide nucleotidyltransferase activity, 3'-5'-exoribonuclease activity, RNA binding, nucleic acid binding; INVOLVED IN: chlorophyll biosynthetic process, cellular response to phosphate starvation, xanthophyll biosynthetic process, carotene biosynthetic process, negative regulation of isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway; LOCATED IN: chloroplast stroma, chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: K Homology, type 1, subgroup (InterPro:IPR018111), Nucleic acid-binding, OB-fold (InterPro:IPR012340), Exoribonuclease, phosphorolytic domain 2 (InterPro:IPR015847), Ribosomal protein S1, RNA-binding domain (InterPro:IPR003029), Polynucleotide phosphorylase, phosphorolytic RNA-binding, bacterial/organelle-type (InterPro:IPR015848), K Homology (InterPro:IPR004087), Nucleic acid-binding, OB-fold-like (InterPro:IPR016027), K Homology, type 1 (InterPro:IPR004088), Exoribonuclease, phosphorolytic domain 1 (InterPro:IPR001247), Ribosomal protein S5 domain 2-type fold (InterPro:IPR020568), Polyribonucleotide nucleotidyltransferase (InterPro:IPR012162); BEST Arabidopsis thaliana protein match is: polyribonucleotide nucleotidyltransferase, putative (TAIR:AT5G14580.1); Has 29137 Blast hits to 25785 proteins in 2865 species: Archae - 377; Bacteria - 19207; Metazoa - 333; Fungi - 67; Plants - 272; Viruses - 0; Other Eukaryotes - 8881 (source: NCBI BLink).
