Encodes an organellar (peroxisome, glyoxysome) 3-ketoacyl-CoA thiolase, involved in fatty acid b-oxidation during germination and subsequent seedling growth. Mutants have defects in glyoxysomal fatty acid beta-oxidation. EC2.3.1.16 thiolase.
Computational Description
peroxisomal 3-ketoacyl-CoA thiolase 3 (PKT3); FUNCTIONS IN: acetyl-CoA C-acyltransferase activity; INVOLVED IN: fatty acid beta-oxidation, jasmonic acid biosynthetic process, response to wounding, fatty acid oxidation, glyoxysome organization; LOCATED IN: in 6 components; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Thiolase (InterPro:IPR002155), Thiolase, active site (InterPro:IPR020610), Thiolase, N-terminal (InterPro:IPR020616), Thiolase, conserved site (InterPro:IPR020613), Thiolase, C-terminal (InterPro:IPR020617), Thiolase-like, subgroup (InterPro:IPR016038), Thiolase-like (InterPro:IPR016039), Thiolase, acyl-enzyme intermediate active site (InterPro:IPR020615); BEST Arabidopsis thaliana protein match is: peroxisomal 3-ketoacyl-CoA thiolase 4 (TAIR:AT1G04710.1); Has 22382 Blast hits to 22371 proteins in 2261 species: Archae - 414; Bacteria - 14116; Metazoa - 985; Fungi - 655; Plants - 282; Viruses - 0; Other Eukaryotes - 5930 (source: NCBI BLink).
