Upstream open reading frames (uORFs) are small open reading frames found in the 5' UTR of a mature mRNA, and can potentially mediate translational regulation of the largest, or major, ORF (mORF). CPuORF2 represents a conserved upstream opening reading frame relative to major ORF AT4G34590.1
Computational Description
conserved peptide upstream open reading frame 2 (CPuORF2); LOCATED IN: endomembrane system; BEST Arabidopsis thaliana protein match is: conserved peptide upstream open reading frame 5 (TAIR:AT1G75388.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
Encodes a basic domain leucine zipper (bZip) transcription factor bZIP11. Translation is repressed by sucrose. Directly regulates gene expression of ASN1 and ProDH2, which are enzyme-coding genes involved in amino acid metabolism.
Computational Description
G-box binding factor 6 (GBF6); FUNCTIONS IN: DNA binding, protein heterodimerization activity, sequence-specific DNA binding transcription factor activity; INVOLVED IN: sucrose induced translational repression, negative regulation of translation, regulation of transcription, DNA-dependent, response to sucrose stimulus; LOCATED IN: chloroplast; CONTAINS InterPro DOMAIN/s: Basic-leucine zipper (bZIP) transcription factor (InterPro:IPR004827), bZIP transcription factor, bZIP-1 (InterPro:IPR011616); BEST Arabidopsis thaliana protein match is: basic leucine-zipper 44 (TAIR:AT1G75390.1); Has 1778 Blast hits to 1778 proteins in 91 species: Archae - 0; Bacteria - 0; Metazoa - 8; Fungi - 2; Plants - 1730; Viruses - 0; Other Eukaryotes - 38 (source: NCBI BLink).